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Accelerated Workflow
Intelligent Analysis
Clinical Cases

Make Every Second Count in Brain Care

Stroke affects one in four people over a lifetime, and the burden is rising with an aging population. In ischemic stroke, timely and accurate assessment is essential, as every minute can mean lost brain function. According to the 2018 AHA guidelines, CT perfusion (CTP) plays a key role in selecting patients for extended mechanical thrombectomy. Compared to MR perfusion, CTP is faster, more accessible, and better suited for emergency care1.

uOmnispace.CT™ Brain Perfusion provides automated, quantitative analysis with a fast and intuitive workflow. It supports confident stroke decisions and also contributes to tumor evaluation where perfusion insights are needed.


[1]. American Heart Association / American Stroke Association (2018) Guidelines for the Early Management of Patients With Acute Ischemic Stroke. 2018;49:e46–e110.

From Scan to Insight in Seconds with Accelerated Perfusion Workflow

Auto pre-processing enables background algorithm matching and execution before the application is opened. It performs essential steps such as bone removal, brain segmentation, and the complete perfusion analysis process—including motion correction, segmentation, vessel definition, parameter calculation, and ischemic penumbra evaluation. This capability streamlines complex workflows, without waiting time, and offers both automatic and manual control options as needed.

Once the perfusion data is received, preprocessing can be automatically initiated. After completion, all results can be previewed directly from the patient management interface. There is no need to open the full application, allowing quick access to key findings and supporting efficient clinical decisions.

Once perfusion parameters are generated, the maps and summary results can be automatically saved for immediate review. This enhances efficiency, speeds up handover, and simplifies case management in time-critical clinical settings.
Accelerate Perfusion Workflow with Advanced Auto Pre-processing

Auto pre-processing enables background algorithm matching and execution before the application is opened. It performs essential steps such as bone removal, brain segmentation, and the complete perfusion analysis process—including motion correction, segmentation, vessel definition, parameter calculation, and ischemic penumbra evaluation. This capability streamlines complex workflows, without waiting time, and offers both automatic and manual control options as needed.

Instant Perfusion Preview with Zero Click

Once the perfusion data is received, preprocessing can be automatically initiated. After completion, all results can be previewed directly from the patient management interface. There is no need to open the full application, allowing quick access to key findings and supporting efficient clinical decisions.

Zero Click Fast-Saving with Automated Preprocessing

Once perfusion parameters are generated, the maps and summary results can be automatically saved for immediate review. This enhances efficiency, speeds up handover, and simplifies case management in time-critical clinical settings.

Instant Access to Full-Spectrum Perfusion Insights

The software automatically extracts time–density curves from dynamic contrast-enhanced data and, in a single step, calculates key perfusion parameters — including CBV, CBF, MTT, TTP, and Tmax — along with precise identification of mismatch volume. The mismatch assessment is aligned with established clinical guidelines from the European Stroke Organization, supporting confident identification of salvageable tissue and guiding treatment strategies in acute ischemic stroke1.

[1]. European Stroke Organisation Guidelines on Intravenous Thrombolysis for Acute Ischaemic Stroke (2021)

For more precise and personalized assessment, the application offers multiple templates to support quantitative evaluation of perfusion data across various clinical scenarios. For clinicians who prefer to manually refine analysis — such as focal mismatch calculation — the software allows adjustment of exclusion thresholds. In cases of chronic cerebrovascular disease or during follow-up assessments, users can evaluate the overall impact of both old and new lesions on cerebral perfusion, gaining deeper insight into disease progression and treatment response.

In addition to acute stroke applications, the CT brain perfusion software includes a dedicated tumor protocol. It calculates key perfusion parameters such as CBV, CBF, TTP, MTT, and PS through a fully automated workflow.

Automated Perfusion and Mismatch Analysis Aligned with Established Clinical Guidelines

The software automatically extracts time–density curves from dynamic contrast-enhanced data and, in a single step, calculates key perfusion parameters — including CBV, CBF, MTT, TTP, and Tmax — along with precise identification of mismatch volume. The mismatch assessment is aligned with established clinical guidelines from the European Stroke Organization, supporting confident identification of salvageable tissue and guiding treatment strategies in acute ischemic stroke1.

[1]. European Stroke Organisation Guidelines on Intravenous Thrombolysis for Acute Ischaemic Stroke (2021)

Customizable Tools for In-Depth Clinical Evaluation

For more precise and personalized assessment, the application offers multiple templates to support quantitative evaluation of perfusion data across various clinical scenarios. For clinicians who prefer to manually refine analysis — such as focal mismatch calculation — the software allows adjustment of exclusion thresholds. In cases of chronic cerebrovascular disease or during follow-up assessments, users can evaluate the overall impact of both old and new lesions on cerebral perfusion, gaining deeper insight into disease progression and treatment response.

Tumor Protocol in CT Brain Perfusion

In addition to acute stroke applications, the CT brain perfusion software includes a dedicated tumor protocol. It calculates key perfusion parameters such as CBV, CBF, TTP, MTT, and PS through a fully automated workflow.

Clinical Case

Acute ischemic stroke

In this case of acute ischemic stroke (left MCA occlusion), the patient presented with right-sided weakness and underwent CT and MRI 3 hours after onset.Non-contrast CT (hypodensity) and DWI (hyperintensity) show a large acute infarct in the left temporo-occipital lobe. CTA confirms occlusion of the left MCA M1 segment.CT perfusion demonstrates a large hypoperfused region, with reduced CBF/CBV and prolonged MTT, TTP, and Tmax. rCBF and Tmax maps show high agreement with the DWI lesion, indicating accurate infarct core delineation.

Acute ischemic stroke

In this case of acute ischemic stroke (right MCA occlusion), the patient underwent CT and MR 1 day after onset of left-sided weakness.
Non-contrast CT shows only small lacunar infarcts near the right lateral ventricle, while DWI reveals new infarction in the right temporo-occipital lobe and periventricular region. CTA demonstrates occlusion of the right MCA M1 segment with absent distal branches.
CT perfusion shows a corresponding hypoperfused area, with reduced CBF/CBV and prolonged MTT, TTP, and Tmax. rCBF and Tmax maps show high agreement with the DWI lesion, confirming accurate infarct core delineation.

Acute ischemic stroke

In this case of acute ischemic stroke (left MCA stenosis), the patient presented with aphasia and right-sided weakness for 15 minutes, with an NIHSS score of 7.
CT perfusion demonstrates a small ischemic core in the left occipital lobe (rCBF < 30%), with a markedly larger hypoperfused penumbra extending throughout the left MCA territory (Tmax > 6s), indicating significant perfusion-diffusion mismatch.
Following balloon angioplasty of the left MCA, the patient achieved good recovery (mRS 0). The perfusion mismatch pattern was consistent with the clinical assessment.

Brain Tumor

Using the brain tumor protocol, automated calculation of tumor-related perfusion parameters is performed, including CBV, CBF, TTP, MTT, and PS.

Acute ischemic stroke

In this case of acute ischemic stroke (left MCA occlusion), the patient presented with right-sided weakness and underwent CT and MRI 3 hours after onset.Non-contrast CT (hypodensity) and DWI (hyperintensity) show a large acute infarct in the left temporo-occipital lobe. CTA confirms occlusion of the left MCA M1 segment.CT perfusion demonstrates a large hypoperfused region, with reduced CBF/CBV and prolonged MTT, TTP, and Tmax. rCBF and Tmax maps show high agreement with the DWI lesion, indicating accurate infarct core delineation.

Acute ischemic stroke

In this case of acute ischemic stroke (right MCA occlusion), the patient underwent CT and MR 1 day after onset of left-sided weakness.
Non-contrast CT shows only small lacunar infarcts near the right lateral ventricle, while DWI reveals new infarction in the right temporo-occipital lobe and periventricular region. CTA demonstrates occlusion of the right MCA M1 segment with absent distal branches.
CT perfusion shows a corresponding hypoperfused area, with reduced CBF/CBV and prolonged MTT, TTP, and Tmax. rCBF and Tmax maps show high agreement with the DWI lesion, confirming accurate infarct core delineation.

Acute ischemic stroke

In this case of acute ischemic stroke (left MCA stenosis), the patient presented with aphasia and right-sided weakness for 15 minutes, with an NIHSS score of 7.
CT perfusion demonstrates a small ischemic core in the left occipital lobe (rCBF < 30%), with a markedly larger hypoperfused penumbra extending throughout the left MCA territory (Tmax > 6s), indicating significant perfusion-diffusion mismatch.
Following balloon angioplasty of the left MCA, the patient achieved good recovery (mRS 0). The perfusion mismatch pattern was consistent with the clinical assessment.

Brain Tumor

Using the brain tumor protocol, automated calculation of tumor-related perfusion parameters is performed, including CBV, CBF, TTP, MTT, and PS.

Disclaimer:

1: The product may not be commercially available in all countries. Please check with your local United Imaging Healthcare representative for availability.

2: This product is intended for use by trained medical professionals only. Please contact your local United Imaging Healthcare organization for further details.